Category: Dementia
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Low-dose niacin supplementation modulates GPR109A, niacin index and ameliorates Parkinson’s disease symptoms without side effects
https://pubmed.ncbi.nlm.nih.gov/26273459/ “In this single-center, double-blind, placebo-controlled, randomized clinical trial comprising patients with early- and late-stage PD, supplementation of a single daily dose of niacin for twelve months improved the rigidity, bradykinesia, and overall UPDRS III scores. High-dose niacin supplement was observed to reduce bradykinesia and rigidity”
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Cognitive frailty among Malaysian older adults: baseline findings from the LRGS TUA cohort study
“Older age, a lower niacin intake, lack of social support, depression and lower functional status were identified as significant factors associated with cognitive frailty” https://www.tandfonline.com/doi/full/10.2147/CIA.S211027